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Full-Length Thymosin Beta-4
The Complete 43-Amino-Acid Peptide for Tissue Regeneration Research
TB-500 is a synthetic 43-amino-acid peptide corresponding to the full sequence of Thymosin Beta-4 (Tβ4) — a naturally occurring protein central to tissue repair and regeneration. Unlike shorter fragments, this complete sequence retains all active regions responsible for actin binding, cell migration, and angiogenesis, making it the definitive tool for comprehensive regenerative research.
- Full 43-amino-acid Thymosin Beta-4 sequence
- Naturally occurring protein involved in tissue repair
- Actin-binding and cell migration properties
- Promotes angiogenesis and wound healing
- High purity for reliable research outcomes
For laboratory research use only. Not for human consumption.
Actin Regulation & Cell Migration
How TB-500 Drives Tissue Repair at the Cellular Level
TB-500 functions primarily through its interaction with G-actin — a key protein that forms the cellular cytoskeleton. By binding to actin, TB-500 promotes cytoskeletal remodeling, enabling cells to migrate toward injury sites. This mechanism drives angiogenesis (new blood vessel formation), accelerates wound closure, and recruits stem and progenitor cells to damaged tissue areas.
- Binds G-actin to promote cytoskeletal remodeling
- Enhances cell migration toward injury sites
- Stimulates angiogenesis and new vessel formation
- Recruits stem and progenitor cells to damaged tissue
- Reduces fibrotic scarring through organized healing
For laboratory research use only. Not for human consumption.
Research Applications
From Musculoskeletal Repair to Cardiac Regeneration Studies
TB-500 has become a cornerstone compound for researchers investigating tissue regeneration across multiple systems. Preclinical studies demonstrate cardioprotective effects — reducing infarct size, promoting neovascularization, and activating cardiac progenitor cells. Its established role in wound healing and anti-fibrotic activity makes it valuable for musculoskeletal, cardiovascular, and soft tissue research.
- Musculoskeletal injury and repair modeling
- Tendon, ligament, and muscle regeneration studies
- Cardiac tissue repair and cardioprotection research
- Wound healing and re-epithelialization studies
- Anti-fibrotic mechanism investigations
- Inflammatory response modulation research
For laboratory research use only. Not for human consumption.
The Science Behind Thymosin Beta-4: Why TB-500 Leads Regenerative Research
TB-500 (Thymosin Beta-4) is a 43-amino-acid peptide that plays a fundamental role in tissue repair and regeneration. Originally identified in the thymus gland, this protein is now known to be expressed in virtually all cell types — functioning as a key regulator of actin dynamics, cell migration, and wound healing processes.
The peptide's mechanism centers on its interaction with G-actin, the monomeric form of the cytoskeletal protein actin. By sequestering G-actin, TB-500 promotes cytoskeletal reorganization — enabling cells to change shape, migrate, and respond to tissue damage. This property is particularly important in angiogenesis, where endothelial cells must migrate and proliferate to form new blood vessels.
Preclinical research demonstrates TB-500's effects across multiple tissue systems. In dermal wound models, it accelerates re-epithelialization by over 40%, enhances collagen deposition, and reduces granulation tissue formation. In cardiac models, it shows cardioprotective effects — preserving cardiac function, reducing infarct volume, and activating endogenous cardiac progenitor cells following ischemic injury. Treated wounds also show superior organized collagen fibers with minimal scarring.
For research teams investigating tissue regeneration, wound healing, cardiac repair, or anti-fibrotic mechanisms, TB-500 provides a well-characterized tool with extensive preclinical literature supporting its biological activity across musculoskeletal, cardiovascular, and soft tissue models.
For research use only. Not for human consumption.
Scientific References
- Malinda KM, et al. Thymosin beta4 accelerates wound healing. J Invest Dermatol. 1999;113(3):364-368.
- Bock-Marquette I, et al. Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature. 2004;432(7016):466-472.
- Ehrlich HP, Bhardwaj N. Thymosin beta4 enhances repair by organizing connective tissue and preventing the appearance of myofibroblasts. Ann N Y Acad Sci. 2010;1194:118-124.
- Treadwell T, et al. The regenerative peptide thymosin β4 accelerates the rate of dermal healing in preclinical animal models and in patients. Ann N Y Acad Sci. 2012;1270:37-44.
- Bollini S, Riley PR, Smart N. Thymosin β4: multiple functions in protection, repair and regeneration of the mammalian heart. Expert Opin Biol Ther. 2015;15 Suppl 1:S163-174.
CERTIFICATE
A detailed summary of the analytical profile, purity, and molecular integrity of the research-grade peptide compound.
Each vial contains a highly purified lyophilized peptide, produced under sterile laboratory conditions and tested for >99% purity via HPLC and mass spectrometry.
Formulated without additives or fillers, our peptides are ideal for cutting-edge scientific research in areas such as cellular mechanisms, tissue regeneration, and metabolic modulation.
For research use only. Not intended for human or veterinary use.
Each batch undergoes rigorous third-party testing to ensure molecular accuracy, sterility, and stability. Our commitment to scientific precision guarantees that every vial reflects the highest standards of quality control and consistency, making them ideal for reproducible and reliable research outcomes.
DIRECTIONS
All peptides are supplied in lyophilized powder form for research use only. Not intended for human or veterinary use.
Use Bacteriostatic Water (0.9%).
Slowly inject the liquid along the inner wall of the vial using a sterile syringe.
Do not shake. Swirl gently until the powder dissolves completely.
Recommended volume depends on your lab protocol (commonly 1–2 mL).
- : Keep lyophilized peptide at 36–46°F, or frozen (-4°F) for long-term stability.
- : Store in the refrigerator (36–46°F) and use within 10 to 30 days, depending on the peptide.
These compounds are intended for Research Use Only.
Always wear gloves and sterile lab gear.
Avoid contamination. Use clean tools and surfaces.
Dispose of all biological materials, including syringes and empty vials, according to your local laboratory safety regulations.
COMPOSITION
An overview of the research characteristics and integrity of the peptide compound.
Each vial contains a highly purified lyophilized peptide, produced under sterile laboratory conditions and tested for >99% purity via HPLC and mass spectrometry.
Formulated without additives or fillers, our peptides are ideal for cutting-edge scientific research in areas such as cellular mechanisms, tissue regeneration, and metabolic modulation.
For research use only. Not intended for human or veterinary use.
Each batch undergoes rigorous third-party testing to ensure molecular accuracy, sterility, and stability. Our commitment to scientific precision guarantees that every vial reflects the highest standards of quality control and consistency, making them ideal for reproducible and reliable research outcomes.
Peptides are shipped as lyophilized powder to ensure maximum stability. Upon arrival, store at -4°F in a dry, dark environment. Once reconstituted, use promptly or refrigerate at 36–46°F for short-term stability. Proper storage preserves biological integrity and ensures reliable research performance over time.
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Tirzepatide – 30mg
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Peptidic.Peptide Sciences
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$108.00$275.00
- ≥99.784%98–99.3%
- 30 mg15 mg
- Free 2-Day Shipping3-10 Business Day
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